With the delta variant spreading in the Bay Area, coronavirus infections have increased sharply. California recently announced that health care workers and state employees must be vaccinated or get tested weekly and wear masks on the job. In late June, San Francisco issued a requirement that city employees and new hires must be vaccinated once available coronavirus vaccines, which currently have emergency use authorization, receive full federal Food and Drug Administration approval. There have already been attempts to challenge vaccine mandates around the nation in court. Dorit Reiss, a law professor at the University of California, Hastings College of the Law who researches legal considerations around vaccines and vaccine mandates, talked with “Civic” about what employers and governments must weigh when it comes to requiring immunization.